06 July 2006

New Beta-Yum yum

Ahhh, another beta version that will never see the light of day. Besides for you, my lone faithful reader.
:) LJS



The effect of subchondral bone (you know, that hard stuff under your cartilage) health on the progression of osteoarthritis is a very cool question. Similar to the “chicken and egg” question, thinking about an answer to these questions may make your head spin. Where does OA start- in the bone or the cartilage? There have been lots of studies to show that it starts in the bone, but there’s an equal amount of studies to show that it starts in the cartilage. So, nobody knows for sure. But, what IS certain is that the role of the subchondral bone in OA progression is more substantial than from what we thought 30 years ago. But then again, we were engaged in the Cold War-so that just might partially explain how silly we used to behave in the 1970’s. In light of all this exciting research, we’re throwing our hats into the fray. We use super cool method R as a non-destructive way to study bone mineral from mousey femurs. Although, I’d hardly call the process of: specimen sacrifice, dissection, and either soaking the leg bone in a bunch of cancerous dyes or zapping it with a laser “non destructive”. I plan on presenting data on how we “non destructively” collect data, and how I’ve interrogated the data more than a guest at Hotel Gitmo. Yes, the data did talk. You’ll have to wait until January to see what they said.

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